腾讯时时彩玩法说明 创新药物研究中心
英文版
 首页  学院概况  师资力量  科学研究  人才培养  学生工作  科研平台  实验室安全  下载专区  联系我们 
 
您的位置: 首页>>师资力量>>课题组>>正文
张传瑞 研究员 课题组
2016-09-07 15:06   审核人:

undefined

张传瑞  研究员

电话:18302335377

邮箱:crzhang@cqu.edu.cn

教育及工作经历

2016.07-至今 腾讯时时彩玩法说明创新药物研究中心,重庆大学百人计划特聘研究员(博士生导师)

2012.01-2015.12 博士后,密歇根州立大学,功能性食品化学,导师Muraleedharan Nair教授

2011.01-2012.01 博士后,亚利桑那大学,植物内生菌天然药物化学,导师Leslie Gunatilaka教授

2010.10-2011.01 副研究员,中国科学院上海药物研究所,天然药物化学

2008.07-2010.10助理研究员,中国科学院上海药物研究所,天然药物化学

2003.09-2008.07 药物化学博士,中国科学院上海药物研究所,师从著名天然药物化学家岳建民研究员

1999.09-2003.07 理学学士,北京师范大学,化学学院应用化学专业


研究领域

  1. 以活性筛选为导向从药用植物中发现具有重要生物活性的小分子化合物,以期发现新药先导化合物进而研发新药;

  2. 以活性筛选为导向从药食两用植物或功能性食品中发现活性物质,以期阐述他们的药用或者功能性作用机制进而开发保健品;

  3. 利用现代科学的理论和手段阐述传统中药的作用机制实现中药现代化。


主持与参与基金

  1. 重庆大学百人计划启动项目(执行期:2016-2019),主持人,在研。

  2. 国家自然科学基金重点项目, 天然产物对雌激素合成和代谢调控机制的研究(20932007),课题主持人,与中国科学院成都生物研究所张国林教授(项目主持人)合作,已结题。

  3. 国家自然科学基金青年科学基金,两种桃花心木属植物中生物活性成分的研究(20902095),主持人,已结题。

  4. 科技部(十二五重大新药创制),规模化中药化学成分库的建立(2011ZX09307-002-03 Y1Z5011030),主要参与人,已结题。

  5. 国家自然科学基金,三种金粟兰属植物化学成分和生物活性的研究(20702057),主要参与人,已结题。

  6. 国家自然科学基金青年科学基金,针对神经退行性疾病新型天然药物先导结构的优化和生物活性研究(20802086),主要参与人,已结题。


获奖情况

2010年上海市自然科学一等奖(排名第四)

2009年中国药学会科学技术奖二等奖(排名第四)

2009年上海药物研究所优秀青年科技工作者

2008年上海药学科技奖一等奖(排名第四)

2008中国科学院朱李月华优秀博士生奖学金


主要代表性论文

  1. Chuan-Rui Zhang, Wajid Khan, Jehan Bakht, Muraleedharan G Nair. New antiinflammatory sucrose esters in the natural sticky coating of tomatillo (Physalis philadelphica), an important culinary fruit. Food Chemistry 2016, 196, 726-732.

  2. Hua Zhang*, Chuan-Rui Zhang*, Ying-Shan Han, Mark A. Wainberg, Jian-Min Yue. New Securinega alkaloids with anti-HIV activity from Flueggea virosa. RSC Advances 2015, 5, 107045-107053. (*Equal contribution)

  3. Chuan-Rui Zhang, Amila A. Dissanayake, Muraleedharan G. Nair. Functional food property of honey locust (Gleditsia triacanthos) flowers. Journal of Functional Foods 2015, 18, 266-274.

  4. Chuan-Rui Zhang, Ettannil Jayashree, Paramasivam Suresh Kumar, Muraleedharan G. Nair. Antioxidant and antiinflammatory compounds in nutmeg (Myristica fragrans) pericarp. Natural Product Communications 2015, 10, 1399-1402.

  5. Chuan-Rui Zhang, Amila A. Dissanayake, Kudret Kevsero?lu, Muraleedharan G. Nair. Evaluation of coriander spice as a functional food by using in vitro bioassays. Food Chemistry 2015, 167, 24-29.

  6. Chuan-Rui Zhang, Saleh A. Aldosari, Polana S. P. V. Vidyasagar, Karun M. Nair, Muraleedharan G. Nair.Antioxidant and anti-inflammatory assays confirm bioactive compounds in ajwa date fruit. Journal of Agricultural and Food Chemistry 2013, 61, 5834-5840.

  7. Chuan-Rui Zhang, Robert E. Schutzki, Muraleedharan G. Nair. Antioxidant and anti-inflammatory compounds in the popular landscape plant Berberis thunbergii var. atropurpurea. Natural Product Communications 2013, 8(2), 165-168.

  8. Chuan-Rui Zhang, Hong-Bing Liu, Shi-Hui Dong, Yan Wu, Jian-Min Yue. Alkaloids from the twigs and leaves ofDaphniphyllum macropodum. Helvetica Chimica Acta 2013, 96, 499-504.

  9. Chuan-Rui Zhang, Cheng-Qi Fan, Shi-Hui Dong, Hong-Bing Liu, Wen-Bin Zhou, Yan Wu, and Jian-Min Yue. Angustimine and angustifolimine, two new alkaloids from Daphniphyllum angustifolium. Organic Letters 2011, 13(9), 2440-2443.

  10. Chuan-Rui Zhang, Yan Wu, and Jian-Min Yue. Polyoxygenated seco-cyclohexene derivatives from Uvaria tonkinensis var. subglabra. Chinese Journal of Natural Medicines 2010, 8(2), 0084-0087.

  11. Chuan-Rui Zhang, Hong-Bing Liu, Shi-Hui Dong, Jian-Yong Zhu, Yan Wu, and Jian-Min Yue. Calycinumines A and B, two novel alkaloids from Daphniphyllum calycinum. Organic Letters 2009, 11(20), 4692-4695. (Hot off the press)

  12. Chuan-Rui Zhang, Hong-Bing Liu, Shi-Hui Dong, Jian-Yong Zhu, Yan Wu, and Jian-Min Yue. Alkaloids from the leaves of Daphniphyllum subverticillatum. Journal of Natural Products 2009, 72(9), 1669-1672.

  13. Chuan-Rui Zhang, Sheng-Ping Yang, Yan Wu, Xue-Qin Chen, Xue-Chu Zhen and Jian-Min Yue. Limonoids from the twigs and leaves of Chukrasia tabularis. Helvetica Chimica Acta 2008, 91(12), 2338-2350.

  14. Chuan-Rui Zhang, Sheng-Ping Yang, Yan Wu, and Jian-Min Yue. Alkaloids from the twigs of Daphniphyllumcalycinum. Journal of Natural Products 2008, 71(10), 1663-1668.

  15. Chuan-Rui Zhang, Cheng-Qi Fan, Li Zhang, Sheng-Ping Yang, Yan Wu, Yang Lu, and Jian-Min Yue. Chuktabrins A and B, two novel limonoids from the twigs and leaves of Chukrasia tabularis. Organic Letters 2008, 10(15), 3183-3186. (Hot off the press)

  16. Chuan-Rui Zhang, Sheng-Ping Yang and Jian-Min Yue. Sterols and triterpenoids from the spores of Ganoderma lucidum. Natural Product Research 2008, 22(13), 1137-1142.

  17. Chuan-Rui Zhang, Sheng-Ping Yang, Shang-Gao Liao, Cheng-Qi Fan, Yan Wu, and Jian-Min Yue. Chuktabularins A-D, four new limonoids with unprecedented carbon skeletons from the stem bark of Chukrasia tabularis. Organic Letters 2007, 9(17), 3383-3386. (Hot off the press)

  18. Chuan-Rui Zhang, Sheng-Ping Yang, Qiao Zhu, Shang-Gao Liao, Yan Wu, and Jian-Min Yue. Nortriterpenoids from Chukrasia tabularis var. velutina. Journal of Natural Products 2007, 70(10), 1616-1619.

  19. Chuan-Rui Zhang, Sheng-Ping Yang, Shang-Gao Liao, Yan Wu, and Jian-Min Yue. Polyoxygenated cyclohexene derivatives from Uvaria rufa. Helvetica Chimica Acta 2006, 89(7), 1408-1416.


关闭窗口

  Copyright © 2005-2017 腾讯时时彩玩法说明•创新药物研究中心 All Rights Reserved 管理登录 技术支持:巨软科技